PARE (MOMORDICA CHARANTIA) FRUIT EXTRACT ANTI-BACTERIAL ACTIVITY TEST AGAINST PSEUDOMONAS AERUGINOSA BACTERIA

Abstract

Pare fruit contains flavonoids which function as antibacterial by forming complex compounds against extracellular proteins that disrupt the integrity of bacterial cell membranes. This study aims to determine the effect of giving the ethanol extract of bitter melon fruit to the Pseudomonas aeruginosa bacteria. This type of research is experimental research. The research design used was the post only control group design. This study used a sample of bitter melon with a concentration of 5%, 4,2%, 2,5%, 1,7% for 6 treatments and 4 repetitions, while for positive control (Ciprofloxacin). And negative control (VCO). From the research that has been done, it is found that the bitter melon extract does not have an inhibitory power against the growth of the bacteria Pseudomonas aeruginosa. The absence of an inhibition zone in the bitter melon extract was caused by factors of differences in the inhibitory test method, the extract drying method used, the extract concentration, and the difference in the content of the bitter melon fruit.